The ‘Central Dogma of Molecular Biology’ enunciated by Francis Crick in 1958 answeres the question about the complex structure and function of the body of animals. A cell, the smallest unit of the body, is composed of ‘proteins’ like a precise machine to form the functional basis of life. The ‘Central Dogma’ describes the series of steps involved in producing ‘function specific’ protein from DNA (a nucleic acid occurs in the cell chromosome) where all the informations about life remain coded. In the first step, the replicating DNA is copied or transcribed as mRNA (messenger RNA) in the cell nucleus with the help of an enzyme called RNA polymerase.The transcribed and processed mRNA then moves from nucleus to the ribosome of cytoplasm where it is decoded or translated into amino acids with the help of tRNA (transfer RNA).The newly formed amino acids are linked together by the aid of various enzymes to form protein for performing specific function exactly in a way it was blueprinted in the source DNA.
Blogger: Sukalpa Das,Masters of Nematology
